diff --git a/src/cmd/go/internal/work/gc.go b/src/cmd/go/internal/work/gc.go
index cc4e2b2b2b..3205fcbffc 100644
--- a/src/cmd/go/internal/work/gc.go
+++ b/src/cmd/go/internal/work/gc.go
@@ -129,7 +129,11 @@ func (gcToolchain) gc(b *Builder, a *Action, archive string, importcfg, embedcfg
 		}
 	}
 
-	args := []interface{}{cfg.BuildToolexec, base.Tool("compile"), "-o", ofile, "-trimpath", a.trimpath(), gcflags, gcargs, "-D", p.Internal.LocalPrefix}
+	args := []interface{}{cfg.BuildToolexec, base.Tool("compile"), "-o", ofile, "-trimpath", a.trimpath(), gcflags, gcargs}
+	if p.Internal.LocalPrefix != "" {
+		// Workaround #43883.
+		args = append(args, "-D", p.Internal.LocalPrefix)
+	}
 	if importcfg != nil {
 		if err := b.writeFile(objdir+"importcfg", importcfg); err != nil {
 			return "", nil, err