diff --git a/src/cmd/compile/internal/reflectdata/reflect.go b/src/cmd/compile/internal/reflectdata/reflect.go
index b3688fca67..e07294be0f 100644
--- a/src/cmd/compile/internal/reflectdata/reflect.go
+++ b/src/cmd/compile/internal/reflectdata/reflect.go
@@ -1475,8 +1475,8 @@ func (a typesByString) Less(i, j int) bool {
 	// will be equal for the above checks, but different in DWARF output.
 	// Sort by source position to ensure deterministic order.
 	// See issues 27013 and 30202.
-	if a[i].t.Kind() == types.TINTER && a[i].t.Methods().Len() > 0 {
-		return a[i].t.Methods().Index(0).Pos.Before(a[j].t.Methods().Index(0).Pos)
+	if a[i].t.Kind() == types.TINTER && a[i].t.AllMethods().Len() > 0 {
+		return a[i].t.AllMethods().Index(0).Pos.Before(a[j].t.AllMethods().Index(0).Pos)
 	}
 	return false
 }
diff --git a/test/fixedbugs/issue46386.go b/test/fixedbugs/issue46386.go
new file mode 100644
index 0000000000..89dea8abf3
--- /dev/null
+++ b/test/fixedbugs/issue46386.go
@@ -0,0 +1,32 @@
+// compile -p=main
+
+// Copyright 2021 The Go Authors. All rights reserved.
+// Use of this source code is governed by a BSD-style
+// license that can be found in the LICENSE file.
+
+package main
+
+type I interface {
+	M() interface{}
+}
+
+type S1 struct{}
+
+func (S1) M() interface{} {
+	return nil
+}
+
+type EI interface{}
+
+type S struct{}
+
+func (S) M(as interface{ I }) {}
+
+func f() interface{ EI } {
+	return &S1{}
+}
+
+func main() {
+	var i interface{ I }
+	(&S{}).M(i)
+}